Rickets following Anticonvulsant Therapy

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منابع مشابه

Rickets associated with anticonvulsant therapy in children with tuberous sclerosis.

Five children with tuberous sclerosis and anti-convulsant-associated rickets have been seen in a general paediatric clinic over the last 5 years. It is suggested that vitamin D prophylaxis is particularly indicated in patients with tuberous sclerosis taking anticonvulsant medication.

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An epidemiological study on vitamin D-dependent rickets was carried out in severely handicapped institutionalised children on long-term anticonvulsant therapy. Nine (10%) of 94 patients had overt rickets on the basis of roentgenological bone changes and biochemical indices, but 46 patients in hospital without medication, and 50 epileptic patients attending an outpatient clinic and taking antico...

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Renal Rickets Following Acquired Nephritis.

In the previous number of the ' Archives of Disease in Childhood,' E. A. Cockayne and F. P. Lee Lander', under the title of ' rickets following an attack of acute nephritis,' recorded a case in which the bony changes of renal rickets had supervened in a previously healthy child who had contracted a severe nephritis. In their comments they remarked on the fact that medical literature contained h...

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Chronic Anticonvulsant Therapy

Branca, M., et al. (1971). Clinical and Experimental Immunology, 9, 853. Brodovsky, H. S., et al. (1968). Archives of Internal Medicine, 121, 71. Froom, D. W., et al. (1972). Archives of Pathology, 94, 547. Hirsch, M. S., Allison, A. C., and Harvey, J. J. (1969). Nature, 223, 739. Holmes, M. C., and Burnet, F. M. (1963). Annals of Internal Medicine, 59, 265. Hyman, L. R., et al. (1973).J_ournal...

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ANTICONVULSANT THERAPY-INDUCED ALTERATIONS IN CALCIUM HOMEOSTASIS

35 epileptic patients, aged 10 to 58 years (mean 23), who were taking anticonvulsant drugs were studied. The patients exhibited a 34% reduction in serum calcium levels, a 41 % increase in serum alkaline phosphatase activity and a slight but insignificant decrease in serum phosphate, compared to untreated controls. These changes appear to be related to the anticonvulsant drug taken, in the ...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society of Medicine

سال: 1972

ISSN: 0035-9157

DOI: 10.1177/003591577206500832